Hydrogen Therapy Shows Promise for Treating Gum Disease
- Authors
- Jiaxun Ying, Keran Zhang, Yangwen Huang, Xinyi Zhu, Yan Ruan, Haiyan Lin, Gang Wu
- Journal
- Medicine
- Year
- 2025
- DOI
- 10.1097/MD.0000000000041800
- Study Type
- clinical
- Peer Reviewed
- Yes
- Country
- China
- Health Condition
- Periodontitis
- Body System
- Oral
TL;DR
Scientists found that a simple gas called molecular hydrogen can help fight tooth and gum disease by reducing harmful inflammation in your mouth—and it could be used as a new treatment before, during, and after gum surgery.
Key Finding
Molecular hydrogen shows potential as an antioxidant agent that may help manage periodontitis by reducing oxidative stress and inflammation in gum tissues.
Summary
This review article examines how molecular hydrogen works to reduce oxidative stress (damage caused by harmful molecules in the body) and explores its potential use in treating periodontitis, a gum disease that damages the tissues supporting teeth. The authors propose a framework for evaluating whether hydrogen should be used in dental treatment before, during, and after gum surgery.
Practical Takeaway
This is a review article summarizing existing research rather than a new study with experimental results, so it cannot establish definitive benefits. While the authors suggest hydrogen therapy may be useful in periodontal treatment, the review does not provide human trial data or specific evidence about hydrogen water's effectiveness for gum health. More rigorous clinical studies would be needed to determine practical applications.
Abstract
Molecular hydrogen, as an effective anti-oxidative stress reagent, has been extensively studied in medicine with new developments continuing to be reported during the years. This review firstly discusses the mechanism of molecular hydrogen of alleviating oxidative stress. Considering the current antioxidant demand in clinical dental treatment, we summarize the progress and future potential of hydrogen's application in periodontitis. Finally, taking its treatment of periodontitis as an example, we develop an Essence-Necessity-Feasibility-Practice (ENFP) benefit evaluation model for whether to introduce new reagents in medical treatment and propose our conclusions on the application of molecular hydrogen before, during, and after periodontal surgeries.