Effect of electrolyzed water on wound healing

A. Murakami, A. Ohmura, C. Ning-Juan, K. Hori, M. Kitahara, M. Kono, N. Yahagi, O. Sumita, P. Woodson, S. Kubota, S. Takamoto, T. Hashimoto

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DOI: 10.1046/j.1525-1594.2000.06557-3.x DOI is the universal ID for this study.

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Electrolyzed water accelerated the healing of full-thickness cutaneous wounds in rats, but only anode chamber water (acid pH or neutralized) was effective. Hypochlorous acid (HOCl), also produced by electrolysis, was ineffective, suggesting that these types of electrolyzed water enhance wound healing by a mechanism unrelated to the well-known antibacterial action of HOCl. One possibility is that reactive oxygen species, shown to be electron spin resonance spectra present in anode chamber water, might trigger early wound healing through fibroblast migration and proliferation.

Publish Year 2000
Country Japan
Rank Positive
Journal Artificial Organs
Primary Topic Skin
Secondary TopicWound Healing
Model Rat
Tertiary TopicOxidative Stress
Vehicle Water (Electrolysis)
pH Mixed
Application Irrigation