Suppressive Effect of High Hydrogen Generating High Amylose Cornstarch on Subacute Hepatic Ischemia-reperfusion Injury in Rats
Hiroki Tanabe, Naomichi Nishimura, Shuhachi Kiriyama, Tatsuro Yamamoto, Yumi Sasaki
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DOI:
10.12938/bmfh.31.103
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Abstract:
We examined whether feeding high hydrogen generating resistant starch could suppress subacute hepatic ischemia-reperfusion injury. Rats were fed a control diet with or without 20% high amylose cornstarch (HAS) supplementation for 14 days. On day 12, rats were subject to ischemia-reperfusion treatment. Portal hydrogen concentration was higher in the HAS group compared with the control group. Increased plasma alanine and aspartate aminotransferase activities due to ischemia-reperfusion treatment tended to decrease, and a significant reduction was observed by HAS feeding when compared with the control group. In conclusion, HAS, which enhances hydrogen generation in the hindgut, alleviated subacute hepatic ischemia-reperfusion injury.
| Publish Year |
2012 |
| Country |
Japan |
| Rank |
Positive |
| Journal |
Bioscience of Microbiota, Food and Health |
| Primary Topic |
Liver |
| Secondary Topic | Surgery/Transplantation |
| Model |
Rat |
| Tertiary Topic | Ischemia-Reperfusion Injury |
| Vehicle |
Gas |
| pH |
N/A |
| Application |
In Vivo Biotic Production |
| Comparison |
|
| Complement |
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