Successful treatment with hydrogen rich water in a case of chronic graft-versus-host-disease

Jian-Liang Shen, Li-Ren Qian

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DOI: 10.4103/2045-9912.191366 DOI is the universal ID for this study.

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The incidence of chronic graft-versus-host-disease is rising year by year, which has become the leading cause of non-transplantation related death and has become the most difficult complication of allogeneic hematopoietic stem cell transplantation to deal with. Inflammation and fibrosis play dominant roles in the pathogenesis of chronic graft-versus-host-disease. Studies have shown that molecular hydrogen has anti-inflammatory, antioxidant, anti-fibrosis effects. Therefore, we hypothesized that molecular hydrogen may have therapeutic effects on chronic graft-versus-host-disease. Here, we report a patient with severe chronic graft-versus-host-disease successfully treated by drinking hydrogen rich water which may be a safe and effective method for chronic graft-versus-host-disease.

Publish Year 2016
Country China
Rank Positive
Journal Medical Gas Research
Primary Topic Bone Marrow
Secondary TopicSurgery/Transplantation
Model Human
Tertiary TopicGraft-Versus-Host-Disease
Vehicle Water (Dissolved)
pH Neutral
Application Ingestion