How to Use Hydrogen Therapy: Different Methods and Applications
Methods of Hydrogen Application
Research hubs: Cardiovascular System · Respiratory System

- Evidence type
- Review or commentary
- Authors
- Li-Ren Qian, Jianliang Shen, Xue-Jun Sun
- Journal
- Hydrogen Molecular Biology and Medicine
- Year
- 2015
- Study Type
- clinical
- Delivery
- mixed
- Peer Reviewed
- Yes
- Cited by
- 2 (OpenAlex, as of November 2026)
- Country
- China
TL;DR
Scientists found that hydrogen gas can help heal the body by reducing damage and swelling, and they figured out safe ways to deliver it to patients through breathing, drinking, injections, and skin treatments. This matters because hydrogen could become a new medicine to treat lots of diseases caused by inflammation and cell damage.
Key Finding
Multiple safe delivery methods for hydrogen gas have been developed, including inhalation, oral hydrogen water, injections, eye drops, topical application, and bathing.
Summary
This review article examines different ways that hydrogen gas can be delivered to the body for medical purposes. Because hydrogen gas is explosive, researchers have developed several safer methods to apply it, including breathing it in, drinking hydrogen-infused water, injections, eye drops, skin applications, and bathing. The article discusses how these different delivery methods have been tested in both laboratory studies and human patients.
Practical Takeaway
This is a review article summarizing existing research methods rather than reporting new experimental results, so it does not provide evidence about hydrogen's effectiveness for any specific health condition. It documents that various delivery methods exist and have been studied, but without access to the actual studies reviewed, it's unclear what evidence supports claims about hydrogen's therapeutic effects.
Abstract (excerpt)
Hydrogen gas has come to the forefront of therapeutic medical gas research. Recent basic and clinical studies have revealed that hydrogen gas is an important physiological regulatory factor, with antioxidant, anti-inflammatory, and antiapoptotic protective effects on cells and organs. Since…