Alkaline Water Slows Aging at the Cellular Level in Mice
- Authors
- Mariantonia Logozzi, Davide Mizzoni, Rossella Di Raimo, Mauro Andreotti, Daniele Macchia, Massimo Spada, Stefano Fais
- Journal
- Journal of Enzyme Inhibition and Medicinal Chemistry
- Year
- 2020
- DOI
- 10.1080/14756366.2020.1733547
- Study Type
- Mouse
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- Italy
- Health Condition
- Aging
- Body System
- Cellular
TL;DR
Drinking alkaline water appears to slow down some molecular signs of aging in mice.
Key Finding
Mice supplemented with alkaline water for 10 months showed reduced oxidative stress, increased antioxidant activity, and longer telomeres compared to control mice.
Summary
Researchers gave aging mice either regular water or alkaline water (water with a higher pH level) for 10 months and then examined aging markers in their blood, bone marrow, and ovaries. Mice drinking alkaline water showed lower levels of harmful molecules called ROS, higher levels of protective antioxidants (SOD-1 and GSH), and longer telomeres (protective caps on DNA that shorten with age) compared to mice drinking regular water.
Practical Takeaway
While this mouse study suggests alkaline water may support cellular aging markers, it cannot be directly applied to humans. Human clinical trials would be needed to determine whether these molecular changes translate to real health benefits in people, and whether alkaline water is safe for long-term use.
Abstract (excerpt)
Telomeres length and telomerase activity are currently considered aging molecular stigmata. Water is a major requirement for our body and water should be alkaline. Recent reports have shown that aging is related to a reduced water intake. We wanted to investigate the effect of the daily intake…