Hydrogen Water Protects Heart from Radiation Damage in Mice
- Authors
- Li-Ren Qian, Fei Cao, Jianguo Cui, Yicun Wang, Yuecheng Huang, Yunhai Chuai, Luqian Zaho, Hao Jiang, Jianming Cai
- Journal
- Journal of Radiation Research
- Year
- 2010
- DOI
- 10.1269/jrr.10093
- Study Type
- Mouse
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- China
- Health Condition
- Radiation-Induced Heart Disease
- Body System
- Cardiovascular
TL;DR
Drinking hydrogen-rich water may protect the heart from damage caused by radiation exposure.
Key Finding
Hydrogen-rich water protected mouse heart tissue from radiation damage by neutralizing harmful free radicals and reducing oxidative stress markers.
Summary
Researchers gave hydrogen-rich water to mice exposed to ionizing radiation (a type of high-energy radiation used in cancer treatment) to see if it could protect their hearts from damage. They found that hydrogen-rich water reduced harmful molecules called hydroxyl radicals and lowered markers of cellular damage in heart tissue, while boosting the body's natural antioxidant defenses.
Practical Takeaway
This is an early-stage animal study suggesting hydrogen-rich water may have potential to protect heart tissue from radiation injury. However, these results are from mice only and have not been tested in humans, so it's too early to draw conclusions about clinical use in cancer patients or others exposed to radiation.
Abstract
Most ionizing radiation-induced damage is caused by hydroxyl radicals, and the selective reduction of hydroxyl by hydrogen in vitro has been demonstrated previously. Irradiation of the heart can cause chronic cardiac disease. This study was designed to test the hypothesis that hydrogen-rich water (pure water saturated with molecular hydrogen), which is easy to use, induces cardioprotection against ionizing irradiation injury in mice. In this paper, we demonstrate that hydrogen can protect myocardium degeneration from radiation-induced injury, decrease myocardium malondialdehyde (MDA), 8-hydroxydeoxyguanosine (8-OHdG) levels, and increase myocardium endogenous antioxidants in vivo. We suggest that hydrogen has a cardioprotective effect against radiation induced injury.