Hydrogen Water Reduces Inflammation in Kidney Dialysis Patients
- Authors
- Masaaki Nakayama, Shigeru Kabayama, Sadayoshi Ito
- Journal
- Renal Replacement Therapy
- Year
- 2016
- DOI
- 10.1186/s41100-016-0036-0
- Study Type
- clinical
- Peer Reviewed
- Yes
- Country
- Japan
- Health Condition
- Chronic Kidney Disease
- Body System
- Renal
TL;DR
Scientists found that adding hydrogen gas to the water used in kidney dialysis treatments helps reduce harmful inflammation and damage in patients' bodies, which could make dialysis safer and help people feel better long-term.
Key Finding
Hemodialysis using hydrogen-enriched water appears to suppress multiple markers of oxidative stress and inflammation in chronic dialysis patients, including reduced interleukin-6 and lymphocyte apoptosis.
Summary
This review examines how hydrogen gas (H2) might help reduce harmful chemical reactions in the bodies of patients undergoing hemodialysis (a kidney treatment). Dialysis patients often experience increased oxidative stress (cellular damage from unstable molecules) and inflammation. Researchers developed a hemodialysis system that delivers water enriched with hydrogen gas, and early studies suggest this approach reduces markers of oxidative stress and inflammation in these patients.
Practical Takeaway
This is a review article summarizing early research rather than a new clinical trial, so evidence remains limited. While animal studies and preliminary clinical observations suggest hydrogen-enriched dialysate may help reduce oxidative stress in dialysis patients, more rigorous human studies are needed to confirm effectiveness and safety. Anyone undergoing dialysis should discuss any new treatment approaches with their nephrologist.
Abstract (excerpt)
Increased oxidative stress and pro-inflammatory conditions, commonly present in chronic dialysis patients, are thought to be enhanced during hemodialysis (HD) and to be associated with the excess morbidity and mortality seen in these patients. The hydrogen molecule (H2) has a unique biological…