Hydrogen Therapy Reduced Joint Inflammation in Arthritic Mice
- Authors
- Yan Tian, Xing Kang, Hao Yang, Shuting Zhang, Yu Wang, Weiping Fan
- Journal
- Chinese Journal of Cellular and Molecular Immunology
- Year
- 2022
- Study Type
- Mouse
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- China
- Health Condition
- Rheumatoid Arthritis
- Body System
- Musculoskeletal
TL;DR
Hydrogen gas treatment reduced arthritis symptoms and inflammation in mice by affecting certain immune cells and signaling pathways.
Summary
Researchers tested the effects of inhaling hydrogen gas on mice with a type of arthritis. They found that the treatment lowered the number of specific immune cells linked to inflammation and decreased the severity of arthritis. The study suggests that hydrogen gas does this by blocking certain pathways that typically lead to increased inflammation and joint damage in arthritis.
Abstract (excerpt)
Objective To investigate the therapeutic effect and mechanism of hydrogen (H2) on collagen-induced arthritis (CIA) in mice. Methods DBA/1 mice were randomly divided into normal control group, CIA group and CIA mice treated with H2 group (H2 treated group), with 6 mice in each group. Following…