Hydrogen Water Protects Pancreas Cells in Diabetic Mice Study
- Authors
- Mi-Ja Kim, Kyung Hee Jung, Yoon Kyung Uhm, Kang-Hyun Leem, Hye Kyung Kim
- Journal
- Biological and Pharmaceutical Bulletin
- Year
- 2007
- DOI
- 10.1248/bpb.30.234
- Study Type
- Mouse
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- South Korea
- Health Condition
- Type 2 Diabetes
- Body System
- Endocrine
TL;DR
Drinking water treated to remove harmful oxygen-containing molecules may help protect insulin-producing cells and lower blood sugar in diabetic mice.
Key Finding
Electrolyzed reduced water reduced blood glucose levels, increased insulin production, and preserved insulin-producing beta cells in diabetic mice, suggesting it may protect against diabetes-related pancreatic damage.
Summary
This study tested electrolyzed reduced water (water treated with electricity to add hydrogen and reduce harmful molecules called free radicals) in genetically diabetic mice. The mice that drank this water showed lower blood sugar levels, higher insulin levels, better glucose tolerance, and preserved pancreatic cells that produce insulin compared to untreated mice.
Practical Takeaway
This is an early-stage animal study showing potential promise for hydrogen-rich water in diabetes management, but it was conducted only in mice—not humans. Much more research, including human trials, would be needed before any conclusions could be drawn about whether this approach would work in people with diabetes.
Abstract
Oxidative stress is produced under diabetic conditions and involved in progression of pancreatic beta-cell dysfunction. Both an increase in reactive oxygen free radical species (ROS) and a decrease in the antioxidant defense mechanism lead to the increase in oxidative stress in diabetes. Electrolyzed reduced water (ERW) with ROS scavenging ability may have a potential effect on diabetic animals, a model for high oxidative stress. Therefore, the present study examined the possible anti-diabetic effect of ERW in genetically diabetic mouse strain C57BL/6J-db/db (db/db). ERW with ROS scavenging ability reduced the blood glucose concentration, increased blood insulin level, improved glucose tolerance and preserved beta-cell mass in db/db mice. The present data suggest that ERW may protects beta-cell damage and would be useful for antidiabetic agent.