Hydrogen Gas Shows Promise for Treating Depression and Anxiety

The Potential of Hydrogen for Improving Mental Disorders

Research hubs: Brain & Nervous System

Evidence type
Review or commentary
Authors
Yasushi Satoh
Journal
Current Pharmaceutical Design
Year
2020
DOI
10.2174/1381612826666201113095938
Study Type
clinical
Peer Reviewed
Yes
Country
Japan
Health Condition
Depression
Body System
Nervous System

TL;DR

Scientists found that a special type of hydrogen gas might help treat mental health problems like depression and anxiety by reducing harmful stress in the brain, and it could work better with fewer side effects than the medications we use today.

Key Finding

Molecular hydrogen shows anti-oxidative, anti-inflammatory, and anti-apoptotic properties that researchers believe could address underlying biological factors in mental disorders, potentially offering an alternative approach to conventional antidepressant and antianxiety medications.

Summary

This review article examines research on molecular hydrogen (H2)—a simple gas that may have health benefits—and its potential use for treating mental health conditions like depression and anxiety. The authors note that H2 appears to reduce harmful molecules called free radicals and inflammation in the body, and they suggest these properties could help prevent or treat mental disorders. However, the review itself does not present new experimental results; instead, it summarizes existing studies and discusses why H2 might work.

Practical Takeaway

This is a review article, not a clinical study with human participants, so it does not provide direct evidence that hydrogen water or H2 gas helps treat mental health conditions in people. While the biological mechanisms described are interesting, actual clinical trials in humans are needed before any health claims can be made. Anyone considering H2 as a mental health treatment should consult their healthcare provider.

Abstract (excerpt)

In 2007, Ohsawa and colleagues reported that molecular hydrogen (H2) gas significantly reduced the infarct volume size in a rat model of cerebral infarction, which was, at least, partially due to scavenging hydroxyl radicals. Since then, multiple studies have shown that H2 has not only…

Read the full abstract via DOI