Medical Gases Show Promise for Stroke Treatment and Brain Protection
- Authors
- Jun-Long Huang, Bao-Lian Zhao, Anatol Manaenko, Fan Liu, Xue-Jun Sun, Qin Hu
- Journal
- Medical Gas Research
- Year
- 2017
- DOI
- 10.4103/2045-9912.208516
- Study Type
- clinical
- Peer Reviewed
- Yes
- Country
- China
- Health Condition
- Stroke
- Body System
- Neurological
TL;DR
Scientists found that special gases like hydrogen and hydrogen sulfide can help protect the brain after a stroke, which is exciting because there aren't many good treatment options for stroke patients right now. They're still figuring out exactly how these gases work, but this could be a whole new way to help people recover from strokes.
Key Finding
Hydrogen and hydrogen sulfide gases demonstrate promising neuroprotective effects in stroke research and represent a potential new therapeutic approach for a condition with very limited current treatment options.
Summary
This review summarizes research from 2015-2016 on using medical gases—including hydrogen—to protect the brain after a stroke. Stroke is a serious condition where blood flow to the brain is blocked, and current treatment options are very limited. The review found that several gases, particularly hydrogen and hydrogen sulfide, show promise in laboratory and animal studies for reducing brain damage after stroke, though the exact mechanisms of how they work are still being studied.
Practical Takeaway
While this review suggests hydrogen gas may have protective effects on brain tissue after stroke, it is based on early-stage research and does not include human clinical trials. Much more research is needed before hydrogen therapy could be considered a viable stroke treatment for patients.
Abstract
Stroke is a cerebrovascular disease with high mortality and morbidity. Despite extensive research, there are only a very limited number of therapeutic approaches suitable for treatment of stroke patients as yet. Mounting evidence has demonstrated that such gases as oxygen, hydrogen and hydrogen sulfide are able to provide neuroprotection after stroke. In this paper, we will focus on the recent two years’ progress in the development of gas therapies of stroke and in understanding the molecular mechanisms underlying protection induced by medical gases. We will also discuss the advantages and challenges of these approaches and provide information for future study.