How Hydrogen Therapy Could Help Protect Your Heart: A Research Overview

Hydrogen therapy and cardiovascular diseases: a visualization analysis of research hotspots and application prospects

Research hubs: Cardiovascular System

Authors
Yi Qian, Mingfei Shi, Yan Yang, Wei Qian, Ziyun Li, Jingqing Hu
Journal
Medical Gas Research
Year
2026
DOI
10.4103/mgr.MEDGASRES-D-25-00165
Study Type
clinical
Peer Reviewed
Yes
Country
China
Health Condition
Cardiovascular Disease
Body System
Cardiovascular

TL;DR

Breathing or drinking hydrogen might help protect your heart by reducing damage from inflammation and other harmful processes in your body. Scientists are excited about this idea, but we still need more real-world studies on actual patients before doctors can start using it as a treatment.

Key Finding

Research on hydrogen therapy for cardiovascular diseases has grown significantly, with ischemia-reperfusion injury and oxidative stress (cellular damage from unstable molecules) being the dominant focus areas — but high-quality human clinical trials remain scarce.

Summary

This study analyzed 162 published papers on hydrogen therapy and heart disease to map out what researchers have studied and where the field is heading. Rather than conducting new experiments, the authors used software tools to identify trends, key topics, and influential researchers in this area. They found that research in this field has grown rapidly, with China, Japan, and the United States leading the way. The most common topics studied include protecting the heart from damage caused by blocked and then restored blood flow (called ischemia-reperfusion injury) and cardiac arrest.

Practical Takeaway

This is a research landscape overview, not a clinical trial, so it doesn't directly tell us whether hydrogen water benefits heart health in people. It suggests that scientific interest in hydrogen for cardiovascular conditions is growing, but the authors themselves emphasize that more rigorous human studies are needed before any clinical conclusions can be drawn.

Abstract (excerpt)

Hydrogen, an emerging medical gas, has demonstrated diverse biological effects, including anti-oxidant, anti-inflammatory, and anti-apoptotic activities, offering significant therapeutic potential in cardiovascular diseases. This study aimed to explore the applications of hydrogen therapy…

Read the full abstract via DOI