Effects of Natural Reduced Water on Cognitive Function, Body Composition, and Psychological Function in Older Adults: Study Protocol for a Randomized Controlled Trial

Hikari Iki, Keisuke Kokubun, Takamitsu Shinada, Yasuyuki Taki, Yuji Takano

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DOI: 10.3390/mps4040073 DOI is the universal ID for this study.

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Natural reduced water is natural water that contains active hydrogen and reduces oxidation. It is rare in the world, and in Japan, it is produced in the Hita area of Oita Prefecture (Hita Tenryosui water). Previous studies in humans have examined the effects of natural reduced water on diabetes, which is one of the known risks for dementia. Animal studies of natural reduced water have revealed anti-obesity and anti-anxiety effects. However, the effects of natural reduced water on cognitive function, body composition, and psychological function in humans are unknown. Therefore, we investigated the relationship between these items in elderly people who continuously consume natural reduced water. In this study, we recruited participants aged between 65 and 74 years. The participants were randomly and blindly assigned to a natural reduced water (Hita Tenryosui water) group or a control (tap water) group and drank 1 L of water daily for 6 months. Cognitive function, body composition, and psychological function were measured before and after the 6-month intervention period.

Publish Year 2021
Country Japan
Rank Neutral
Journal Methods and Protocols
Primary Topic Brain
Secondary TopicAging
Model Human
Tertiary TopicCognitive Impairment
Vehicle Water, Commercial (Hita Tenryosui)
pH Alkaline
Application Ingestion