Hydrogen Gas Inhalation Improves Brain Health in Adults of All Ages
- Authors
- Md. Habibur Rahman, Johny Bajgai, Subham Sharma, Eun-Sook Jeong, Seong Hoon Goh, Yeon-Gyu Jang, Cheol-Su Kim, Kyu-Jae Lee
- Journal
- Antioxidants
- Year
- 2023
- DOI
- 10.3390/antiox12061241
- Study Type
- Human
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- South Korea
- Health Condition
- Alzheimer's Disease
- Body System
- Nervous System
TL;DR
Breathing in hydrogen gas for four weeks improved brain health and reduced signs of stress and inflammation in adults, suggesting it could help people with Alzheimer's disease.
Key Finding
Four weeks of hydrogen gas inhalation was safe and well-tolerated in adults of various ages, with no adverse effects on immune cells, while reducing oxidative stress markers and improving several dementia-related biomarkers.
Summary
Researchers gave 54 community-dwelling adults hydrogen gas to inhale for 4 weeks to see if it was safe and might help with Alzheimer's disease and thinking problems. The treatment was well-tolerated with no harmful effects on immune cells. Blood tests showed that hydrogen gas inhalation reduced markers of cellular damage (oxidative stress) and improved several biological markers associated with dementia and brain health.
Practical Takeaway
This early-stage human study suggests hydrogen gas inhalation may be worth further investigation for cognitive health, but important limitations apply: the study had no control group for comparison, was relatively short (4 weeks), and measured blood biomarkers rather than actual cognitive improvements. Larger, controlled trials would be needed before drawing conclusions about real-world benefits for Alzheimer's disease or cognitive decline.
Abstract (excerpt)
Molecular hydrogen (H2) is a versatile therapeutic agent. H2 gas inhalation is reportedly safe and has a positive impact on a range of illnesses, including Alzheimer's disease (AD). Herein, we investigated the effects of 4 weeks of H2 gas inhalation on community-dwelling adults of various ages…