Magnesium Hydride Shows Promise for Hydrogen Therapy Treatment

Authors
Journal
Magnesium Alloys - Selected Issue
Year
DOI
10.5772/intechopen.79507
Study Type
clinical
Peer Reviewed
Yes
Country
Taiwan
Health Condition
Oxidative Stress
Body System
Cellular

TL;DR

Scientists discovered that hydrogen gas can help protect our cells from damage, and they found a new way to deliver it using a compound called magnesium hydride—which can carry twice as much hydrogen as older methods, making it a potentially better treatment option for diseases caused by cellular damage.

Key Finding

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Summary

Scientists investigated magnesium hydride as an improved method for delivering hydrogen therapy. Traditional metallic magnesium has limited hydrogen storage capacity, but magnesium hydride hydrolysis can double this capacity. The study highlights hydrogen's therapeutic potential, including antioxidant, anti-inflammatory, and antiapoptotic effects that protect cells from damage. Multiple delivery methods exist for hydrogen therapy, including gas inhalation, hydrogen water consumption, and hydrogen-saturated saline injection. Hydrogen-water produced through magnesium hydride hydrolysis emerged as particularly promising for on-demand therapeutic use. The research suggests this approach could effectively combat oxygen-derived free radicals and oxidative stress in cellular environments.

Abstract

Oxygen sustains the lives of human a unique element. However, oxygen is unwanted and harmful when it is over tension to introduce oxygen-derived free radicals in the cells. Hydrogen and oxygen are both involved in the genesis of life that exists on Earth and metabolism in vivo, so it is not strange to exert a biological effect. Recently, scientists have found that hydrogen is an essential physiological regulatory function with antioxidant, anti-inflammatory, and antiapoptotic protective effects on cells. Using therapeutic hydrogen includes different delivery methods, such as inhalation of hydrogen gas, oral hydrogen water, and injection of hydrogen-saturated saline. In clinical applications, magnesium hydride hydrolysis instead of traditional metallic magnesium is effective in increasing the theoretical hydrogen storage capacity by two times. The hydrogen-water comes across as being an excellent choice to produce from magnesium hydride hydrolysis on-demand because its antioxidant activity cannot store.