Hydrogen Water Reduces Inflammation in Kidney Dialysis Patients
- Authors
- Masaaki Nakayama, Shigeru Kabayama, Hirofumi Nakano, Wan-Jun Zhu, Hiroyuki Terawaki, Keisuke Nakayama, Kiyoshi Katoh, Toshinobu Satoh, Sadayoshi Ito
- Journal
- Nephron Clinical Practice
- Year
- 2009
- DOI
- 10.1159/000210569
- Study Type
- Human
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- Japan
- Health Condition
- Chronic Kidney Disease
- Body System
- Renal
TL;DR
Adding hydrogen gas to dialysis solutions helped reduce inflammation and blood pressure in patients undergoing hemodialysis.
Key Finding
Hydrogen-enriched dialysis solution reduced inflammatory markers and improved blood pressure control in hemodialysis patients, with 62% achieving target blood pressure after 6 months compared to 21% at baseline.
Summary
Researchers tested whether adding hydrogen gas to dialysis solution could help hemodialysis patients, who often suffer from chronic inflammation (persistent swelling and immune activation). Over 6 months, 21 patients used dialysis machines with hydrogen-enriched solution instead of standard solution. The treatment was safe, and patients showed improvements: more patients achieved healthy blood pressure levels (62% vs. 21% at the start), and blood tests showed reduced markers of inflammation.
Practical Takeaway
This small human study suggests hydrogen-enriched dialysis may help manage inflammation and blood pressure in kidney disease patients undergoing dialysis. However, the study involved only 21 patients and lasted 6 months, so larger and longer studies are needed to confirm these results and determine if benefits persist over time. This approach is currently experimental and not standard treatment.
Abstract (excerpt)
Background/Aims: The application of electrolyzed water (EW) at the cathode side to manufacture reverse osmosis (RO) water and hemodialysis (HD) solution can actually lead to less oxidative capacity in chemical terms. The present study examined the biological actions of this water on human…