Hydrogen Drink Shows Promise for Treating Brain Injuries and Concussions
- Authors
- Tyler W. LeBaron, Jason Kharman, Michael L. McCullough
- Journal
- Journal of Integrative Neuroscience
- Year
- 2021
- DOI
- 10.31083/j.jin2003071
- Study Type
- Human
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- United States
- Health Condition
- Traumatic Brain Injury
- Body System
- Nervous System
TL;DR
A drink called Hydro Shot containing molecular hydrogen may help protect the brain from injury after a traumatic brain injury (TBI).
Key Finding
An H2-infused, nitric oxide-producing beverage may theoretically address multiple harmful processes that occur after traumatic brain injury by leveraging hydrogen's ability to cross the blood-brain barrier and modulate inflammation, oxidative stress, and nitric oxide metabolism.
Summary
This study examined whether a beverage containing hydrogen gas and nitric oxide could help protect the brain after traumatic injuries. Traumatic brain injuries cause inflammation, oxidative stress (cellular damage from unstable molecules), and reduced blood flow to the brain. The researchers propose that hydrogen, because of its small size, can cross the blood-brain barrier (a protective filter around the brain) and reduce inflammation and cellular damage, while also helping regulate nitric oxide, another protective molecule. The study reports preliminary indications that this beverage may offer benefits, but detailed results are not yet available.
Practical Takeaway
This is a very early-stage, preliminary study with no reported sample size or duration, so firm conclusions cannot be drawn. While the theoretical basis is interesting, there is currently insufficient human evidence to support using this beverage as a treatment for brain injuries. Anyone with a concussion or TBI should follow standard medical care and consult a healthcare provider before considering experimental interventions.
Abstract (excerpt)
Traumatic brain injuries (TBIs) are a leading cause of death and disability. Sports-related TBIs are estimated to be more than several million per year. The pathophysiology of TBIs involves high levels of inflammation, oxidative stress, dysregulation of ion homeostasis, mitochondrial dysfunction…