The Suppressive Effect of Electrolyzed Reduced Water on Lipid Peroxidation
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DOI:
10.1007/978-94-017-0726-8_66
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Abstract:
We examined the suppressive effect on lipid peroxidation of electrolyzed reduced water (ERW), which exhibited reactive oxygen species (ROS)-scavenging activity in vitro and in cultured cells. The oxidation of linoleic acid by 2, 2’-azobis (2-amidinopropane) hydrochloride (AAPH) was suppressed by ERW in vitro. ERW also suppressed the lipid peroxidation in cell membrane of mouse lymphoblast YAC-1 cells. Transparent electron microscopic analysis revealed that platinum in ERW existed as a colloidal form of nm size. Concentrated ERW suppressed the lipid peroxidation in a manner dependent upon the concentration of platinum nanocolloids, and chemical synthesized platinum nanocolloids exhibited a similar suppressive effect on lipid peroxidation to that of ERW, suggesting that platinum nanocolloids contained in ERW were reducing agents to suppress the lipid peroxidation.| Publish Year | 2003 |
|---|---|
| Country | Japan |
| Rank | Positive |
| Journal | Animal Cell Technology: Basic and Applied Aspects |
| Primary Topic | Whole Body |
| Secondary Topic | Dyslipidemia |
| Model | Cell Culture |
| Tertiary Topic | Oxidative Stress |
| Vehicle | Water (Electrolysis) |
| pH | Alkaline |
| Application | Culture Media |
| Comparison | |
| Complement | Platinum |