Suppressive Effect of ERW on Lipid Peroxidation and Plasma Triglyceride Level

Kazuko Toh, Kiichiro Teruya, Masumi Abe, Noboru Nakamichi, Sanetaka Shirahata, Shinkatsu Morisawa, Shunpei Sato, Takeki Hamasaki, Yoshinori Katakura

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DOI: 10.1007/978-90-481-3892-0_52 DOI is the universal ID for this study.

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Electrolyzed reduced water (ERW) containing hydrogen molecules and Pt nanoparticles is expected as a new antioxidant. Thiobarbituric acid reactive substances (TBARS) assay revealed that ERW had an inhibitory effect on the oxidation of low-density lipoproteins (LDL). In addition, ERW significantly suppressed LDL oxidation in the medium cultured J.774.A1 macrophage like cells. ERW inhibited Cu2+ ion-catalyzed oxidation of LDL ex vivo. ERW lowered lipid peroxide level in blood red cells and plasma triglyceride in rats fed a basal diet containing 2% cholesterol. These results suggest that ERW has anti-LDL oxidation and anti-hyperlipidemia effects.

Publish Year 2010
Country Japan
Rank Positive
Journal Animal Cell Technology: Basic and Applied Aspects
Primary Topic Whole Body
Secondary TopicDyslipidemia
Model Rat
Tertiary TopicOxidative Stress
Vehicle Water (Electrolysis)
pH Alkaline
Application Mixed
Complement Platinum