Redox Regulation by Reduced Waters as Active Hydrogen Donors and Intracellular ROS Scavengers for Prevention of type 2 Diabetes
Read more:
DOI:
10.1007/978-1-4020-5476-1_15
DOI is the universal ID for this study.
This link will take you to the full study.
Abstract:
The analysis using the DBNBS reduction method and the DCFH-DA intracellular reactive oxygen species (ROS) determination method revealed that ERW and diseases-improvable natural waters such as Nordenau water in Germany and Hita water in Japan were all reduced waters (RWs) which could function as active hydrogen donors and intracellular ROS scavengers. RWs suppressed the activity of protein tyrosine phosphatase (PTP), which inactivates insulin receptor, suggesting their anti-type 2 diabetes effects via redox regulation. The clinical test of 356 diabetes patients drinking Nordenau water in Germany resulted in the improvement of the relevant tests parameters after 6 days, suggesting the correlation of these changes with the fluctuation of ROS levels in their blood.| Publish Year | 2007 |
|---|---|
| Country | Japan |
| Rank | Positive |
| Journal | Cell Technology for Cell Products |
| Primary Topic | Whole Body |
| Secondary Topic | Diabetes (Type II) |
| Model | Human |
| Tertiary Topic | Oxidative Stress |
| Vehicle | Water, Commercial (Nordenau) |
| pH | Alkaline |
| Application | Ingestion |
| Comparison | |
| Complement |