How Your Gut Bacteria Naturally Produce Hydrogen Gas

Authors
Journal
New England Journal of Medicine
Year
DOI
10.1056/NEJM196907172810303
Study Type
Human
Outcome
Neutral
Peer Reviewed
Yes
Country
United States
Health Condition
Small Bowel Bacterial Overgrowth
Body System
Gastrointestinal

TL;DR

Scientists found that the human gut produces more hydrogen gas, especially in the colon, when people eat or drink certain sugars like lactose, and some of this gas is breathed out, which can help measure gut activity.

Key Finding

Intestinal hydrogen production in humans is primarily a colonic process driven by bacterial fermentation of carbohydrates, and breath hydrogen levels correlate strongly (r = 0.94) with actual intestinal hydrogen production.

Summary

Researchers studied how much hydrogen gas the human intestine produces by measuring it directly and tracking it in breath. They found that hydrogen production is normally very low when fasting, but increases dramatically after eating, especially after consuming lactose (a sugar in milk). Most hydrogen is produced in the colon (large intestine) by bacteria breaking down food, and about 14% of the hydrogen produced is exhaled in breath, which correlates closely with how much is being made in the gut.

Practical Takeaway

This foundational study explains how hydrogen gas naturally forms in the human digestive system through bacterial fermentation of food. While it establishes that breath hydrogen testing can measure intestinal hydrogen production, this research does not address hydrogen water consumption or its health effects—it simply describes the body's own hydrogen gas production as a normal digestive process.

Abstract (excerpt)

Technics employing intestinal infusions of gas were used to study H2 production in the human intestine. The volume of H2 in the bowel of 10 normal subjects varied from 0.06 to 29 ml. H2 production, which averaged 0.24 ml per minute in the fasting state, sharply increased after intestinal…

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