Hydrogen Gas Safe for Head and Neck Cancer Patients During Treatment
- Authors
- Imjai Chitapanarux, Wimrak Onchan, Somvilai Chakrabandhu, Pooriwat Muangwong, Narongchai Autsavapromporn, Tapanut Ariyanon, Junji Akagi, Akira Mizoo
- Journal
- OncoTargets and Therapy
- Year
- 2024
- DOI
- 10.2147/OTT.S478613
- Study Type
- Human
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- Thailand
- Health Condition
- Head and Neck Cancer
- Body System
- Respiratory
TL;DR
Breathing in hydrogen gas appears to be a safe and doable treatment to reduce side effects for patients undergoing chemotherapy and radiation for advanced head and neck cancer.
Key Finding
Hydrogen gas inhalation was feasible and safe in all 10 patients with no adverse events directly caused by the hydrogen gas, with stable vital signs maintained throughout 33 daily inhalation sessions.
Summary
Researchers tested whether inhaling hydrogen gas during cancer treatment could be done safely and tolerated by patients. Ten patients with advanced head and neck cancer inhaled hydrogen gas daily for one hour while undergoing radiation and chemotherapy treatment. All patients completed the treatment without any side effects from the hydrogen gas itself, and their vital signs remained stable throughout.
Practical Takeaway
This is a very small pilot study (only 10 patients) that only tested whether hydrogen gas inhalation is safe to use alongside cancer treatment—it did not measure whether it actually reduces radiation side effects. While the safety results are encouraging, much larger studies would be needed to determine if hydrogen gas provides any therapeutic benefit for cancer patients. This research is too early-stage to draw conclusions about hydrogen gas for general health use.
Abstract (excerpt)
Purpose: Hydrogen (H2) gas inhalation might alleviate acute radiotherapy toxicities by scavenging free radicals produced by ionizing radiation and anti-inflammatory properties. This study aimed to investigate the feasibility and safety of H2 gas inhalation during concurrent chemoradiotherapy (CCRT)…