Hydrogen Water Protects Gut Health in Pigs Fed Contaminated Feed
Morphological and molecular response of small intestine to lactulose and hydrogen-rich water in female piglets fed Fusarium mycotoxins contaminated diet
Research hubs: Digestive System
- Evidence type
- Animal study (pig)
- Authors
- Xu Ji, Qing Zhang, Weijiang Zheng, Wen Yao
- Journal
- Journal of Animal Science and Biotechnology
- Year
- 2019
- DOI
- 10.1186/s40104-019-0320-2
- Study Type
- Pig
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- China
- Health Condition
- Leaky Gut Syndrome
- Body System
- Digestive
This research was done in animals. Results in animals often don't carry over to people.
TL;DR
Giving piglets hydrogen-rich water (HRW) or lactulose (LAC) can protect their intestines from damage caused by eating feed contaminated with Fusarium mycotoxins.
Key Finding
Hydrogen-rich water reduced intestinal damage from mycotoxin-contaminated feed by decreasing cell death, restoring the integrity of the intestinal barrier, and normalizing protein expression in piglet intestines.
Summary
This study tested whether hydrogen-rich water could protect piglets' intestines from damage caused by eating feed contaminated with Fusarium mycotoxins (toxic substances produced by mold). Researchers divided 24 female piglets into four groups: one ate clean feed, while the others ate contaminated feed with or without hydrogen-rich water or lactulose treatment. The piglets given hydrogen-rich water showed better intestinal health, with less cell death, better intestinal lining structure, and improved function of proteins that hold intestinal cells together compared to piglets that only ate contaminated feed.
Practical Takeaway
While this animal study suggests hydrogen-rich water may help protect intestines from mycotoxin damage, these results are from piglets only and cannot be directly applied to humans. The study does not tell us whether hydrogen water would have similar protective effects in people or at what doses it might be effective. More research in humans would be needed before drawing conclusions about health benefits.
Abstract (excerpt)
Background Following the intake of Fusarium mycotoxin-contaminated feed, small intestines may be exposed to high levels of toxic substances that can potentially damage intestinal functions in livestock. It is well known that Fusarium mycotoxins will lead a breakdown of the normally impeccable…