Hydrogen Therapy Helps Brain Bleeding Patient with Autoimmune Disease
Molecular Hydrogen Therapy in Aneurysmal SAH With RA and Newly-diagnosed SLE, Complicated With Acute Ischemic Infarction: A Case Report of Improved Immune Markers Including Tr1 Cells, Breg Cells and TIM3 Expression on Tc Cells
Research hubs: Rheumatoid Arthritis · Brain & Nervous System · Cardiovascular System
- Evidence type
- Case report or series · Human study
- Authors
- Jing-Yuan Chen, Jeng-Wei Lu, Shao-Wei Feng, Yi-Jung Ho, Shan-Wen Lui, Ting-Yu Hsieh, Feng-Cheng Liu
- Journal
- In Vivo
- Year
- 2024
- PMID
- 39477420
- Study Type
- Human
- Participants
- 1
- Delivery
- Gas (Sustained Release)
- Dose
- daily treatment with hydrogen capsules
- H₂ concentration
- 0.6 mM per 200 ml of water
- Funding
- Ministry of Science and Technology (MOST 111-2314-B-016-026); National Science and Technology Council (NSTC 112-2314-B-016-033); National Science and Technology Council (NSTC 113-2314-B-016-052); Tri-Service General Hospital (TSGH-E-111215); Tri-Service General Hospital (TSGH-E-112218)
- Conflicts of interest
- None declared
- Outcome
- Positive
- Peer Reviewed
- Yes
- Cited by
- 4 (OpenAlex, as of November 2026)
- Country
- Taiwan
TL;DR
A woman with a brain bleed and autoimmune diseases improved after treatment with hydrogen capsules, suggesting a new potential therapy.
Key Finding
A single patient with a severe brain bleed and autoimmune disease showed stabilization of symptoms and improvements in immune markers after receiving daily hydrogen capsules, though this is a case report of one person rather than a controlled study.
Summary
This report describes a single patient with a life-threatening brain bleed (subarachnoid hemorrhage) who also had two autoimmune diseases and a stroke. After standard treatments did not fully help, she received hydrogen capsules daily. Her immune system markers improved, including increases in certain protective immune cells, and a blood test related to her autoimmune disease changed from abnormal to normal. Her symptoms stabilized without reported side effects.
Practical Takeaway
This is a single case report, not a controlled study, so it cannot prove hydrogen therapy works for this condition. While the patient's outcome was positive, case reports describe what happened in one person and cannot establish whether hydrogen caused the improvement or whether it would help others. Much larger and more rigorous studies would be needed before drawing any conclusions about hydrogen's effectiveness for brain bleeds or autoimmune disease.
Abstract (excerpt)
Background/aim: Most nontraumatic subarachnoid hemorrhages (SAHs) are caused by ruptured saccular aneurysms, often resulting in a devastating clinical event characterized by high mortality and significant morbidity among survivors. Numerous studies have confirmed the neuroprotective effects…