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Hydrogen Gas Helps COVID Recovery in New Study

Molecular Hydrogen Positively Affects Physical and Respiratory Function in Acute Post-COVID-19 Patients: A New Perspective in Rehabilitation

Research hubs: Respiratory System · Cardiovascular System

Scientific visualization of hydrogen therapy research for Molecular Hydrogen Positively Affects Physical and Respiratory Function in Acute Post-COVID-19 Patients: A New Perspective in Rehabilitation
Evidence type
Randomized controlled trial · Human study
Authors
Michal Botek, Jakub Krejčí, Michal Valenta, Andrew McKune, Barbora Sládečková, Petr Konečný, Iva Klimešová, Dalibor Pastucha
Journal
International Journal of Environmental Research and Public Health
Year
2022
Study Type
Human
Participants
50
Delivery
Gas
Dose
2 × 60 min/day for 14 days
H₂ concentration
99.99% purity
Duration
2 weeks
Funding
Palacký University Olomouc (IGA_FTK_2021_009); BALUO Application Centre of Faculty of Physical Culture, Palacký University Olomouc
Conflicts of interest
None declared
Outcome
Positive
Peer Reviewed
Yes
Cited by
56 (OpenAlex, as of November 2026)
Country
Czech Republic

TL;DR

Breathing in hydrogen gas for two weeks helped improve lung function and physical ability in patients who had recently recovered from COVID-19.

Key Finding

People recovering from acute COVID-19 who inhaled molecular hydrogen for 14 days walked significantly farther in a 6-minute walking test and showed improved lung function measurements compared to those who received placebo.

Summary

This study tested whether breathing molecular hydrogen gas could help people recovering from COVID-19. Fifty people who were 3-5 weeks into their recovery breathed either hydrogen gas or a placebo (fake treatment) for 2 hours each day over 14 days. Researchers measured how far participants could walk in 6 minutes and tested their lung function. People who breathed hydrogen gas walked farther and showed improvements in lung function compared to those who received the placebo.

Practical Takeaway

This small, short-term study suggests hydrogen gas inhalation may support recovery of physical and respiratory function in early post-COVID-19 recovery. However, the study involved only 50 people and lasted just 2 weeks, so larger and longer studies would be needed to confirm these results and determine if benefits persist. More research is also needed to understand how hydrogen might work and whether it helps people with long-term COVID symptoms.

Abstract (excerpt)

Molecular hydrogen (H2) is potentially a novel therapeutic gas for acute post-coronavirus disease 2019 (COVID-19) patients because it has antioxidative, anti-inflammatory, anti-apoptosis, and antifatigue properties. The aim of this study was to determine the effect of 14 days of H2 inhalation…

Read the full abstract on PubMed