Hydrogen Gas Shows Promise for Stem Cell Therapy and Tissue Healing
Molecular Hydrogen: From Molecular Effects to Stem Cells Management and Tissue Regeneration

- Evidence type
- Review or commentary
- Authors
- Mikhail Yu. Artamonov, Andrew K. Martusevich, Felix A. Pyatakovich, Inessa A. Minenko, Sergei V. Dlin, Tyler W. LeBaron
- Journal
- Antioxidants
- Year
- 2023
- PMID
- 36978884
- Study Type
- clinical
- Peer Reviewed
- Yes
- Cited by
- 41 (OpenAlex, as of November 2026)
- Country
- Russia
TL;DR
Scientists reviewed thousands of studies and found that a simple gas called hydrogen might be really good at helping our bodies heal and fix damaged tissues, especially by working with special cells that can grow into any type of cell we need.
Key Finding
A systematic review of over 2,000 studies indicates that molecular hydrogen produces diverse biological effects across multiple cell and tissue types, with particular potential in stem cell applications and regenerative medicine.
Summary
This review article summarizes over 2,000 published studies on molecular hydrogen—a simple gas that can be introduced into the body through various methods. Researchers found that hydrogen appears to have multiple biological effects on different types of cells, including stem cells (cells that can develop into specialized cell types). The review suggests that hydrogen's effects on cells and tissues make it worth investigating further as a potential tool in regenerative medicine (medical approaches that aim to repair or replace damaged tissues and organs).
Practical Takeaway
While this review identifies hydrogen as a promising research direction, it is a summary of existing literature rather than new experimental evidence. The authors themselves note that further systematic research is needed to establish specific clinical protocols and determine actual effectiveness in treating human conditions. Anyone interested in hydrogen water should recognize that this represents early-stage research potential, not proven clinical benefit.
Abstract (excerpt)
It is known that molecular hydrogen is a relatively stable, ubiquitous gas that is a minor component of the atmosphere. At the same time, in recent decades molecular hydrogen has been shown to have diverse biological effects. By the end of 2022, more than 2000 articles have been published…