Hydrogen Gas Protects DNA from Radiation Damage in Lab Study

Hydrogen gas can significantly protect DNA from damage caused by gamma radiation by capturing harmful molecules known as hydroxyl radicals.

Dissolved hydrogen gas reduced radiation-induced DNA damage in laboratory solutions by scavenging hydroxyl radicals, the primary damaging molecules created by gamma radiation exposure.

Researchers exposed DNA to gamma radiation in laboratory solutions and tested whether dissolved hydrogen gas could protect the DNA from damage. They found that hydrogen significantly reduced radiation-induced damage to DNA building blocks by neutralizing harmful molecules called hydroxyl radicals (reactive oxygen species created by radiation). The protective effect was specific to hydrogen—helium gas had no protective effect—showing that hydrogen works by capturing these damaging radicals rather than through other mechanisms.

This is an early-stage laboratory study in test tubes, not human research, so it cannot yet support health claims about hydrogen water for radiation protection. The findings suggest hydrogen may have radioprotective properties at the molecular level, but much more research—including animal and human studies—would be needed to determine whether drinking hydrogen water could provide similar protection in living organisms.

Purpose: The main aim of the present study is to gain mechanistic insights into the modulating effect of molecular hydrogen on the γ-radiation-induced alteration pathways of DNA nucleobases. Materials and methods: Aerated aqueous solutions of calf thymus DNA were exposed to a (60)Co source at doses…

Read the full abstract on PubMed