Hydrogen Water Speeds Burn Healing by Activating Skin Repair Cells

Mast Cells in Regeneration of the Skin in Burn Wound with Special Emphasis on Molecular Hydrogen Effect

Research hubs: Skin & Dermatology System · Immune System

Evidence type
Animal study (rat)
Authors
Dmitri Atiakshin, Mariya Soboleva, Dmitry Nikityuk, Nataliya Alexeeva, Svetlana Klochkova, Andrey Kostin, Viktoriya Shishkina, Igor Buchwalow, Markus Tiemann
Journal
Pharmaceuticals
Year
2023
DOI
10.3390/ph16030348
Study Type
Rat
Outcome
Positive
Peer Reviewed
Yes
Country
Russia
Health Condition
Second-degree Burns
Body System
Integumentary System

This research was done in animals. Results in animals often don't carry over to people.

TL;DR

Breathing in molecular hydrogen can help heal second-degree burn wounds faster by boosting the repair of the skin's connective tissue.

Key Finding

Molecular hydrogen treatment stimulated collagen formation and accelerated skin regeneration in rat burn wounds, with effects comparable to standard therapeutic ointments.

Summary

Researchers studied how molecular hydrogen (hydrogen gas dissolved in water) affects burn wound healing in rats, focusing on mast cells (immune cells involved in tissue repair). They found that treating second-degree burns with hydrogen-enriched water stimulated the growth of collagen (a protein that gives skin its structure) and accelerated healing, with results comparable to standard wound ointments.

Practical Takeaway

This rat study suggests hydrogen-enriched water may support burn wound healing by activating tissue repair processes, though human studies are needed to confirm whether these results apply to people. The study's small scope and animal-only design mean the findings cannot yet guide clinical decisions.

Abstract (excerpt)

The mechanisms of regeneration for the fibrous component of the connective tissue of the dermis are still insufficiently studied. The aim of this study was to evaluate the effectiveness of the use of molecular hydrogen on the local therapy of a II degree burn wound with the intensification…

Read the full abstract via DOI