Hydrogen Gas Inhalation Reduces Asthma Symptoms in Mice Study
Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice
Research hubs: Respiratory System
- Evidence type
- Animal study (mouse)
- Authors
- Ning Zhang, Changwen Deng, Xingxing Zhang, Jingxi Zhang, Chong Bai
- Journal
- Asthma Research and Practice
- Year
- 2018
- DOI
- 10.1186/s40733-018-0040-y
- Study Type
- Mouse
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- China
- Health Condition
- Allergic Asthma
- Body System
- Respiratory
This research was done in animals. Results in animals often don't carry over to people.
TL;DR
Breathing in hydrogen gas helped improve lung function and reduce airway inflammation in mice with asthma-like symptoms.
Key Finding
Inhaling hydrogen gas reduced lung resistance, decreased inflammatory cells and immune markers in asthmatic mice, and boosted the body's natural antioxidant defenses.
Summary
Researchers tested whether breathing hydrogen gas could help mice with allergic asthma. Asthmatic mice that inhaled high-concentration hydrogen gas for one hour daily for a week showed improvements in lung function, less inflammation in their airways, and reduced markers of cellular damage (oxidative stress) compared to untreated asthmatic mice.
Practical Takeaway
This early-stage animal study suggests hydrogen gas inhalation may help reduce airway inflammation and oxidative stress in asthma, but much more research is needed before any conclusions can be drawn for humans. The study was conducted only in mice, so results may not translate directly to people with asthma.
Abstract (excerpt)
Background Asthma is a worldwide common chronic airway disease that cannot be cured and results in the huge burden in public health. Oxidative stress was considered an important mechanism in the pathogenesis of asthma. Hydrogen gas been demonstrated to function as a novel antioxidant and exert…