Hydrogen Water Fights Chronic Fatigue in Mice Study
Hydrogen Water Drinking Exerts Antifatigue Effects in Chronic Forced Swimming Mice via Antioxidative and Anti-Inflammatory Activities
Research hubs: Chronic Fatigue · Oxidative Stress
- Evidence type
- Animal study (mouse)
- Authors
- Jesmin Ara, Ailyn Fadriquela, Md Faruk Ahmed, Johny Bajgai, Ma Easter Joy Sajo, Sung Pyo Lee, Tae Su Kim, Jin Young Jung, Cheol Su Kim, Soo-Ki Kim, Kwang Yong Shim, Kyu-Jae Lee
- Journal
- BioMed Research International
- Year
- 2018
- DOI
- 10.1155/2018/2571269
- Study Type
- Mouse
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- South Korea
- Health Condition
- Chronic Fatigue
- Body System
- Muscular
This research was done in animals. Results in animals often don't carry over to people.
TL;DR
Drinking hydrogen water improved the endurance and reduced fatigue in mice that were made to swim regularly.
Key Finding
Mice drinking hydrogen water showed significantly greater swimming endurance and reduced fatigue markers compared to mice drinking regular water, with improvements linked to better metabolic balance and reduced inflammation.
Summary
Researchers gave mice either regular water or hydrogen-enriched water while subjecting them to daily swimming stress for 4 weeks. Mice drinking hydrogen water swam longer before becoming exhausted and showed better recovery markers—including lower blood sugar and lactate (a fatigue byproduct) and higher energy stores in the liver. The hydrogen water also reduced inflammatory molecules and boosted the body's natural antioxidant defenses (proteins that neutralize harmful molecules).
Practical Takeaway
This mouse study suggests hydrogen water may help with fatigue recovery by reducing inflammation and supporting antioxidant defenses, but results from animal studies don't automatically apply to humans. Much larger human trials would be needed before drawing conclusions about hydrogen water's effectiveness for chronic fatigue in people.
Abstract (excerpt)
Purpose. This study was performed to evaluate antifatigue effect of hydrogen water (HW) drinking in chronic forced exercise mice model. Materials and Methods. Twelve-week-old C57BL6 female mice were divided into nonstressed normal control (NC) group and stressed group: (purified water/PW-treated…