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Hydrogen Water vs Coffee: Better Sleep Deprivation Relief Without Jitters

Hydrogen vs. Caffeine for Improved Alertness in Sleep-Deprived Humans

Research hubs: Brain & Nervous System

Scientific visualization of hydrogen therapy research for Hydrogen vs. Caffeine for Improved Alertness in Sleep-Deprived Humans
Evidence type
Randomized controlled trial · Human study
Authors
D. Zanini, V. Stajer, S. M. Ostojic
Journal
Neurophysiology
Year
2020
Study Type
Human
Participants
23
Delivery
Water (Mg-Chemico)
Dose
single-dose hydrogen-rich water
Duration
1 day or less
Outcome
Positive
Peer Reviewed
Yes
Country
Serbia

TL;DR

Drinking hydrogen-rich water (HRW) might be as effective as caffeine in temporarily making sleep-deprived young adults feel more alert, without any side effects.

Key Finding

Hydrogen-rich water increased alertness in sleep-deprived people by a similar amount as caffeine, with no reported side effects compared to caffeine's negative effects on attention.

Summary

In this small study, researchers gave 23 sleep-deprived young adults either hydrogen-rich water or caffeine and measured how alert they felt and how well they performed on attention tests. Both hydrogen-rich water and caffeine increased alertness similarly (by about 1.6–1.7 points on a rating scale). Caffeine caused some drops in attention and focus in follow-up tests, while hydrogen-rich water caused only a small change in one attention measure. Neither treatment was clearly better than the other overall.

Practical Takeaway

This is a very small pilot study (23 people, 24-hour sleep deprivation only), so the results are preliminary. While hydrogen-rich water showed promise as a caffeine alternative with fewer side effects, much larger and longer studies are needed before drawing firm conclusions about its real-world usefulness for alertness.

Abstract (excerpt)

Molecular hydrogen (H2) has been suggested as an agent capable of exerting neuromodulating effects; yet, its potential to affect brain circuits linked to alertness remains poorly examined. In this randomized controlled cross-over pilot trial, we compared acute effects of single-dose hydrogen-rich…

Read the full abstract via DOI