Hydrogen Water May Help High-Altitude Sickness Patients
- Authors
- Qian Zhang, Fengying Zhang, Yang Zhong, Qiuyue Li, Doudou Hao, Zhiyou Shi, Suying Zhu, Yunhong Wu, Xiaonan Yue
- Journal
- Food Research International
- Year
- 2025
- DOI
- 10.1016/j.foodres.2025.117118
- Study Type
- Human
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- China
- Health Condition
- Chronic High-Altitude Disease
- Body System
- Immune System
TL;DR
Drinking hydrogen-rich water for 60 days showed early signs of reducing inflammation and oxidative stress in people with chronic high-altitude disease.
Key Finding
Hydrogen-rich water treatment significantly downregulated inflammation and cytokine-related gene pathways in chronic high-altitude disease patients, whereas placebo water did not produce these molecular changes.
Summary
This study tested whether hydrogen-rich water could help people with chronic high-altitude disease (a condition caused by living at high elevations where the body experiences oxidative stress—cellular damage from unstable molecules—and inflammation). Forty-three patients drank either hydrogen-rich water or regular water for 60 days. Researchers found that hydrogen-rich water appeared to reduce inflammation-related genes and showed a downward trend in inflammatory markers, though the changes were not statistically significant.
Practical Takeaway
While this study suggests hydrogen-rich water may help manage chronic high-altitude disease at the genetic level, the actual improvements in inflammation and oxidative stress markers were small and not statistically significant. The study was also relatively small (43 participants) and short (60 days), so larger and longer studies are needed before drawing firm conclusions about whether hydrogen-rich water would meaningfully help people with this condition.
Abstract (excerpt)
Chronic high-altitude disease (CHAD) is primarily driven by oxidative damage and inflammation. Hydrogen-rich water (HRW) is a novel functional food with demonstrated antioxidant and anti-inflammatory properties. However, its potential effects on inflammation and oxidative stress in CHAD remain…