Hydrogen Water Protects Against Cell Damage and Restores Health in Mice
Hydrogen-Rich Alkaline Water Supplementation Restores a Healthy State and Redox Balance in H2O2-Treated Mice
Research hubs: Oxidative Stress · Immune System
This research was done in animals. Results in animals often don't carry over to people.
- Evidence type
- Animal study (mouse)
- Authors
- Davide Mizzoni, Mariantonia Logozzi, Rossella Di Raimo, Massimo Spada, Stefano Fais
- Journal
- International Journal of Molecular Sciences
- Year
- 2024
- PMID
- 38928440
- Study Type
- Mouse
- Delivery
- Water (Electrolysis)
- Dose
- daily intake of hydrogen-rich alkaline water for two weeks
- Duration
- 2 weeks
- Outcome
- Positive
- Peer Reviewed
- Yes
- Cited by
- 1 (OpenAlex, as of November 2026)
- Country
- Italy
TL;DR
Drinking hydrogen-rich alkaline water reduced oxidative stress and DNA damage in mice treated with a harmful substance.
Key Finding
Hydrogen-rich alkaline water reduced harmful free radicals and DNA damage in mice exposed to hydrogen peroxide, while increasing the body's natural antioxidant defenses.
Summary
Researchers gave mice hydrogen-rich alkaline water to see if it could counteract damage caused by hydrogen peroxide, a chemical that creates harmful molecules called free radicals in the body. Mice that drank the hydrogen-rich water showed lower levels of these harmful molecules, higher levels of a natural antioxidant called glutathione, and less damage to their DNA compared to untreated mice.
Practical Takeaway
This study was conducted only in mice exposed to a specific chemical stressor, so it cannot be directly applied to human health. While the results suggest hydrogen-rich water may have antioxidant effects in this controlled laboratory setting, human studies would be needed to determine whether similar benefits occur in people under normal conditions.
Abstract (excerpt)
Water is a major requirement for our bodies, and alkaline water has induced an antioxidant response in a model of natural aging. A series of recent reports have shown that aging is related to reduced water intake. Hydrogen-rich water has been suggested to exert a general antioxidant effect…