Hydrogen Gas Reduces Airway Inflammation in Asthma and COPD Patients

Authors
Journal
QJM: An International Journal of Medicine
Year
DOI
10.1093/qjmed/hcaa164
Study Type
Human
Outcome
Positive
Peer Reviewed
Yes
Country
China
Health Condition
Asthma
Body System
Respiratory

TL;DR

Breathing in hydrogen-rich steam for 45 minutes reduced signs of inflammation in the airways of people with asthma and COPD.

Key Finding

A single 45-minute inhalation of 2.4% hydrogen gas reduced multiple airway inflammation markers in both asthma and COPD patients, including MCP-1 in both groups and IL-8 in asthma patients.

Summary

Researchers tested whether inhaling a mixture containing 2.4% hydrogen gas for 45 minutes could reduce airway inflammation in patients with asthma and COPD (a lung disease that makes breathing difficult). They measured inflammatory markers (chemical signals that indicate inflammation) in the blood and breath before and after the treatment. The hydrogen inhalation reduced several inflammation markers in both groups, suggesting it may have anti-inflammatory effects in the airways.

Practical Takeaway

This small human study suggests hydrogen gas inhalation may have acute anti-inflammatory effects in people with asthma and COPD. However, this was a single short treatment in only 20 patients total, so it's unclear whether repeated use would be beneficial or safe long-term. More research is needed before this could be considered a practical therapy.

Abstract (excerpt)

Summary Background Hydrogen was proven to have anti-oxidative and anti-inflammation effects to various diseases. Aim We wish to investigate the acute effects of inhaled hydrogen on airway inflammation in patients with asthma and chronic obstructive pulmonary disease (COPD). Design Prospective…

Read the full abstract via DOI