Hydrogen Gas Shrinks Advanced Gallbladder Cancer in 72-Year-Old Woman
Hydrogen gas therapy induced shrinkage of metastatic gallbladder cancer: A case report
Research hubs: Digestive System
- Evidence type
- Case report or series · Human study
- Authors
- Ji-Bing Chen, Zhong-Bao Pan, Duan-Ming Du, Wei Qian, Yang-Yang Ma, Feng Mu, Ke-Cheng Xu
- Journal
- World Journal of Clinical Cases
- Year
- 2019
- PMID
- 31423439
- Study Type
- Human
- Participants
- 1
- Delivery
- Gas
- Dose
- daily hydrogen inhalation therapy
- H₂ concentration
- 67% hydrogen
- Duration
- 4 months
- Conflicts of interest
- None declared
- Outcome
- Positive
- Peer Reviewed
- Yes
- Cited by
- 18 (OpenAlex, as of November 2026)
- Country
- China
TL;DR
A 72-year-old woman with advanced gallbladder cancer showed improvement after inhaling hydrogen gas, despite other treatments failing.
Key Finding
A patient with metastatic gallbladder cancer who was unresponsive to standard treatments showed tumor shrinkage, correction of anemia, and clinical stability after three months of daily hydrogen gas inhalation therapy.
Summary
This report describes a single 72-year-old woman with advanced gallbladder cancer that had spread to her liver and lymph nodes and was not responding to standard treatments. After she began inhaling hydrogen gas daily, her tumors started to shrink over three months, her severe anemia improved, and she was able to return to normal activities. However, this is just one patient's experience, not a controlled study.
Practical Takeaway
While this single case report is intriguing, it provides very limited evidence. A single patient's response cannot establish whether hydrogen therapy actually caused the improvement or whether other factors were involved. Much larger, controlled studies would be needed before any conclusions could be drawn about hydrogen's effectiveness for cancer patients.
Abstract (excerpt)
Background: We present the case of a 72-year-old female patient with gallbladder cancer (GBC) who developed in situ recurrence and liver metastases 9 mo after irreversible electroporation ablation and oral tegafur (a fluoropyrimidine derivative) chemotherapy, which failed to control the progression…