How Hydrogen Gas Spreads Through Body Organs After Breathing

Authors
Journal
Scientific Reports
Year
DOI
10.1038/s41598-018-38180-4
Study Type
Rat
Outcome
Neutral
Peer Reviewed
Yes
Country
Japan
Health Condition
Whole Body
Body System
Cardiovascular

TL;DR

Researchers found that hydrogen gas reaches different levels and saturates at different times in various organs when inhaled by rats, which helps understand how it might work as a treatment.

Key Finding

Hydrogen gas distributes unevenly across rat organs when inhaled, with the liver accumulating the highest concentration and muscle tissue taking significantly longer to saturate with hydrogen than other organs.

Summary

Researchers tracked how hydrogen gas spreads through different organs in rats after the animals breathed in 3% hydrogen gas. They measured hydrogen levels in the brain, liver, kidney, fat, and muscle using a sensitive sensor. The liver accumulated the most hydrogen, while the kidney accumulated the least. Muscle tissue took much longer to reach maximum hydrogen levels (about 20 minutes) compared to other organs (6-9 minutes).

Practical Takeaway

This rat study provides basic information about how inhaled hydrogen gas moves through the body, which may help explain how hydrogen could potentially affect different organs. However, this is early-stage research in animals only, and it's unclear whether these distribution patterns would be the same in humans or whether they translate to actual health benefits.

Abstract (excerpt)

Hydrogen has therapeutic and preventive effects against various diseases. Although animal and clinical studies have reported promising results, hydrogen distribution in organs after administration remains unclear. Herein, the sequential changes in hydrogen concentration in tissues over time were…

Read the full abstract via DOI