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HYDROGEN STUDIESPOWERED BY ECHO WATER

How Gut Bacteria Use Hydrogen to Impact Digestive Health

Hydrogen cross-feeders of the human gastrointestinal tract

Research hubs: Digestive System

Scientific visualization of hydrogen therapy research for Hydrogen cross-feeders of the human gastrointestinal tract
Evidence type
Review or commentary
Authors
Nick W. Smith, Paul R. Shorten, Eric H. Altermann, Nicole C. Roy, Warren C. McNabb
Journal
Gut Microbes
Year
2018
Study Type
clinical
Peer Reviewed
Yes
Cited by
167 (OpenAlex, as of November 2026)
Country
New Zealand

TL;DR

Your gut bacteria produce hydrogen gas, and other bacteria eat that hydrogen and turn it into different chemicals—some good, some bad for your health. Scientists think controlling these hydrogen-eating bacteria could help treat belly problems like irritable bowel syndrome.

Key Finding

Three functional groups of hydrogen-consuming gut bacteria coexist in the human digestive tract and convert hydrogen into different compounds that may influence gastrointestinal health and disease.

Summary

This review examines how hydrogen gas produced by gut bacteria is used by other bacteria in the human digestive system. Three types of bacteria consume this hydrogen and convert it into different compounds: hydrogen sulfide, methane, and acetate. The balance between these three groups may influence digestive health, and research suggests that too much hydrogen sulfide or methane production could be linked to conditions like irritable bowel syndrome.

Practical Takeaway

This is a review article summarizing current knowledge about gut bacteria and hydrogen metabolism, not a study testing hydrogen water or a specific intervention. It suggests that understanding hydrogen metabolism in the gut may eventually lead to new treatments for digestive conditions, but much more research is needed to determine how to safely target these bacteria.

Abstract (excerpt)

Hydrogen plays a key role in many microbial metabolic pathways in the human gastrointestinal tract (GIT) that have an impact on human nutrition, health and wellbeing. Hydrogen is produced by many members of the GIT microbiota, and may be subsequently utilized by cross-feeding microbes for growth…

Read the full abstract on PubMed