Hydrogen Gas Helps Sleep Apnea Brain Problems in Rats
- Authors
- Wenya Li, Shengchang Yang, Fu-Yang Yu, Yashuo Zhao, Zhi-Min Sun, Ji-ren an, En-Sheng Ji
- Journal
- Brain Research Bulletin
- Year
- 2018
- DOI
- 10.1016/j.brainresbull.2018.09.012
- Study Type
- Rat
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- China
- Health Condition
- Obstructive Sleep Apnea
- Body System
- Nervous System
TL;DR
Breathing hydrogen gas can help improve memory and brain function in rats that have a sleep disorder similar to sleep apnea.
Key Finding
Hydrogen gas inhalation improved memory and learning problems in rats exposed to chronic low-oxygen conditions, apparently by reducing oxidative stress and preventing brain cell death.
Summary
This study tested whether breathing hydrogen gas could help rats recover from memory and thinking problems caused by sleep apnea-like conditions (repeated drops in oxygen while sleeping). Rats exposed to low oxygen for 5 weeks showed memory problems, but those also given hydrogen gas for 2 hours daily performed better on memory tests. The researchers found that hydrogen reduced harmful molecules called oxidative stress in the brain and prevented brain cell death in the memory center (hippocampus).
Practical Takeaway
This early animal study suggests hydrogen gas may have protective effects on the brain during low-oxygen stress, but these results are from rats only and have not been tested in humans. Much more research would be needed before hydrogen could be considered a treatment for sleep apnea or related cognitive problems in people.
Abstract (excerpt)
Obstructive sleep apnea (OSA) is a very common breathing and sleep disorder characterized by intermittent hypoxia (IH), which is often associated with behavioral and neurocognitive functions impairment. Hydrogen (H2), as a novel and effective antioxidant, is reported to be a potential…