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Probiotic Milk in Lab Tests Survived Digestion

Fermented Milk Supplemented with Sodium Butyrate and Inulin: Physicochemical Characterization and Probiotic Viability Under In Vitro Simulated Gastrointestinal Digestion

Research hubs: Digestive System

This research was done on cells or tissue in a lab, not in people or animals.

Scientific visualization of hydrogen therapy research for Fermented Milk Supplemented with Sodium Butyrate and Inulin: Physicochemical Characterization and Probiotic Viability Under In Vitro Simulated Gastrointestinal Digestion
Evidence type
Laboratory study (cells or tissue)
Authors
Katarzyna Szajnar, Małgorzata Pawlos, Magdalena Kowalczyk, Julita Drobniak, Agata Znamirowska-Piotrowska
Journal
Nutrients
Year
2025
Study Type
Cell Culture
Delivery
Gas (Sustained Release)
Outcome
Positive
Peer Reviewed
Yes
Cited by
3 (OpenAlex, as of November 2026)
Country
Poland

TL;DR

Adding inulin and sodium butyrate to probiotic milk helped probiotics survive digestion and maintained good taste and texture.

Summary

This study tested how inulin and sodium butyrate affected probiotic milk’s quality and the survival of beneficial bacteria during digestion. The combination did not harm probiotic viability and, depending on the strain, influenced acidity, texture, and consumer acceptability. These results support using inulin-butyrate fortified dairy products to improve gut health without compromising product quality.

Abstract (excerpt)

Background/Objectives: Probiotics are increasingly recognized for their role in managing gastrointestinal disorders through modulation of gut microbiota. Restoring microbial balance remains a therapeutic challenge. Recent strategies combine probiotics, inulin, and sodium butyrate as synergistic…

Read the full abstract on PubMed