Electrolyzed Water Shows Promise Against Chagas Disease in Mice Study
Electrolyzed Oxidizing Water Modulates the Immune Response in BALB/c Mice Experimentally Infected with Trypanosoma cruzi
Research hubs: Immune System · Cardiovascular System
This research was done in animals. Results in animals often don't carry over to people.

- Evidence type
- Animal study (mouse)
- Authors
- Olivia Rodríguez-Morales, Juan José Cabrera-Mata, Silvia del C. Carrillo-Sánchez, Rodolfo A. Gutiérrez-Ocejo, Lidia Baylón-Pacheco, Olga L. Pérez-Reyes, José Luis Rosales-Encina, Alberto Aranda-Fraustro, Sergio Hernández-García, Minerva Arce-Fonseca
- Journal
- Pathogens
- Year
- 2020
- PMID
- 33238401
- Study Type
- Mouse
- Delivery
- Water (Electrolysis)
- Outcome
- Neutral
- Peer Reviewed
- Yes
- Cited by
- 4 (OpenAlex, as of November 2026)
- Country
- Mexico
TL;DR
A study found that Electrolyzed Oxidizing Water (EOW) can help reduce the severity of Chagas disease in mice by boosting certain immune responses.
Key Finding
Electrolyzed oxidizing water reduced parasite levels and mortality in infected mice as effectively as the standard drug benznidazole, working primarily by strengthening the immune response rather than directly attacking the parasite.
Summary
Researchers tested electrolyzed oxidizing water (water treated with electricity to create specific chemical properties) in mice infected with a parasite that causes Chagas disease. The treated mice showed reduced parasite levels, better overall health, and lower death rates compared to untreated mice. The water appeared to work by boosting the immune system rather than directly killing the parasite.
Practical Takeaway
This is an early-stage animal study that does not directly apply to humans or hydrogen water specifically. While the results are interesting for understanding how electrolyzed water might affect immune function, much more research—including human trials—would be needed before any conclusions could be drawn about its use for Chagas disease or other conditions in people.
Abstract (excerpt)
Chagas disease is a major public health problem in Latin America. The mixed Th1/Th2 immune response is required against Trypanosoma cruzi. Electrolyzed oxidizing water (EOW) has been shown to have germicidal efficacy. The objective of this study was to evaluate the EOW effectiveness in T…