Hydrogen Water Reduces Candida Biofilm in Lab Cell Studies
Efficacy of newly developed denture cleaning device on physical properties of denture material and Candida biofilm
Research hubs: Digestive System
This research was done on cells or tissue in a lab, not in people or animals.
- Evidence type
- Laboratory study (cells or tissue)
- Authors
- Young-Gyun Song, Sung-Hoon Lee
- Journal
- Journal of Dental Sciences
- Year
- 2019
- PMID
- 31528252
- Study Type
- Cell Culture
- Delivery
- Water (Electrolysis)
- Duration
- 5 months
- Outcome
- Positive
- Peer Reviewed
- Yes
- Cited by
- 19 (OpenAlex, as of November 2026)
- Country
- South Korea
TL;DR
A denture cleaning device using electrolyzed water effectively kills fungus on dentures without significantly damaging them.
Key Finding
The electrolyzed water denture cleaning device effectively reduced Candida albicans biofilm on denture material while causing minimal changes to surface roughness and color, though it did slightly reduce the material's hardness after 150 days of use.
Summary
This study tested a new denture cleaning device that uses electrolyzed water (water treated with electricity to create antimicrobial properties) to clean dentures and kill Candida albicans, a fungus that can grow on denture surfaces. Researchers compared this device to chemical denture cleaners by testing how well each removed the fungus and how they affected the physical properties of denture material over 150 days. Both the electrolyzed water device and chemical cleanser successfully reduced fungus growth, and the electrolyzed water device did not significantly damage the denture surface, though it did slightly reduce the material's hardness.
Practical Takeaway
This laboratory study suggests that electrolyzed water devices may offer a gentler alternative to chemical denture cleaners, particularly for elderly users who might misuse harsh chemicals. However, this research was conducted in a laboratory setting on denture material samples, not in human mouths, so real-world effectiveness and safety would need to be confirmed in human studies. The slight reduction in material hardness over time is a consideration for long-term use that warrants further investigation.
Abstract (excerpt)
Background/purpose: Electrolyzed water has antimicrobial activity against oral microbes. The purpose of this study was to investigate the effects of a denture cleaning device that uses electrolyzed water on Candida biofilm on denture base-material and the physical properties of the denture…