Special Acidic Water Accelerates Wound Healing in Mice Study
Effects of Strong Acidic Electrolyzed Water in Wound Healing via Inflammatory and Oxidative Stress Response
Research hubs: Skin & Dermatology System
This research was done in animals. Results in animals often don't carry over to people.

- Evidence type
- Animal study (mouse)
- Authors
- Ailyn Fadriquela, Ma Easter Joy Sajo, Johny Bajgai, Dong-Heui Kim, Cheol-Su Kim, Soo-Ki Kim, Kyu-Jae Lee
- Journal
- Oxidative Medicine and Cellular Longevity
- Year
- 2020
- PMID
- 33414890
- Study Type
- Mouse
- Delivery
- Water (Electrolysis)
- Dose
- Sprayed three times a day for seven days
- Duration
- 1 weeks
- Outcome
- Positive
- Peer Reviewed
- Yes
- Cited by
- 21 (OpenAlex, as of November 2026)
- Country
- South Korea
TL;DR
Strong acidic electrolyzed water (StAEW) significantly improves wound healing in mice by influencing inflammation and tissue repair processes.
Key Finding
Strong acidic electrolyzed water accelerated wound healing in mice compared to saline and alcohol controls, with faster reduction of inflammatory markers and better management of oxidative stress.
Summary
Researchers tested a special acidic water created through electrolysis (a process using electrical current) on wound healing in mice. The treated wounds healed faster than wounds treated with saline (salt water) or alcohol, and the acidic water appeared to reduce inflammation and oxidative stress (cellular damage from unstable molecules) while promoting the growth of new tissue.
Practical Takeaway
While this mouse study suggests acidic electrolyzed water may have wound-healing properties, it is not yet tested in humans and should not be used as a medical treatment without clinical trials. The connection to hydrogen water specifically is unclear, as this study focused on the acidic properties of electrolyzed water rather than hydrogen content.
Abstract (excerpt)
Strong acidic electrolyzed water (StAEW) is known to inactivate microorganisms but is not fully explored in the medical field. This study is aimed at exploring StAEW as a potential wound care agent and its mechanism. StAEW (pH: 2.65, ORP: 1159 mV, ACC: 32.1 ppm) was sprayed three times a day…