Hydrogen Water Lowers Uric Acid in High Uric Acid Patients
Effects of hydrogen-rich water on blood uric acid in patients with hyperuricemia: A randomized placebo-controlled trial
- Evidence type
- Randomized controlled trial · Human study
- Authors
- Fenglin Wu, Jun Ma, Junli Xue, Xue Jiang, Jinyu Liu, Jiashuo Zhang, Yazhuo Xue, Boyan Liu, Shucun Qin
- Journal
- Heliyon
- Year
- 2024
- PMID
- 39258191
- Study Type
- Human
- Participants
- 100
- Delivery
- Water (Electrolysis)
- Dose
- Low-HRW: 660 mL/day (2 bottles HRW + 1 bottle ordinary water); High-HRW: 990 mL/day (3 bottles HRW) for 8 weeks
- H₂ concentration
- ≥4.66 mg/L
- Duration
- 8 weeks
- Funding
- National Natural Science Foundation of China [82200508, 81770855]; Science and Technology Support Plan for Youth Innovation Team of Universities in Shandong Province [2023KJ184]; Academic Promotion Programme of Shandong First Medical University [2019QL010]
- Conflicts of interest
- None declared
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- China
TL;DR
Drinking high doses of hydrogen-rich water (HRW) for 8 weeks can significantly lower blood uric acid levels in people with hyperuricemia.
Key Finding
After 8 weeks of consuming high-dose hydrogen-rich water, participants with hyperuricemia experienced a significant reduction in blood uric acid levels compared to baseline, with greater effectiveness at higher doses than lower doses.
Summary
Researchers tested whether drinking hydrogen-rich water (water infused with hydrogen gas) could lower uric acid levels in people with hyperuricemia (abnormally high blood uric acid). Over 8 weeks, 100 participants either drank regular water or hydrogen-rich water at low or high doses. The group drinking high-dose hydrogen-rich water showed a meaningful reduction in blood uric acid levels compared to their starting levels, with better results than the low-dose group.
Practical Takeaway
This small human study suggests that hydrogen-rich water may help lower uric acid levels in people with hyperuricemia, particularly at higher doses. However, the study involved only 100 people and lasted 8 weeks, so longer-term safety and effectiveness remain unclear. Anyone with hyperuricemia should discuss this with their doctor before using hydrogen-rich water as part of their treatment plan.
Abstract (excerpt)
Background: Consumption of hydrogen-rich water (HRW) has been shown to have anti-inflammatory and metabolic-modulatory benefits. Objective: A randomized, placebo-controlled trial was conducted to assess the potential blood uric acid-lowering effects of HRW consumption with different doses (low…