Hydrogen Water Reduces Liver Fat in High-Fat Diet Study

Authors
Journal
World Journal of Gastroenterology
Year
DOI
10.3748/wjg.v24.i45.5095
Study Type
Mouse
Outcome
Positive
Peer Reviewed
Yes
Country
Israel
Health Condition
Non-Alcoholic Fatty Liver Disease
Body System
Hepatic

TL;DR

Drinking water with high levels of hydrogen gas can reduce fat build-up in the liver and improve body composition in mice on a high-fat diet.

Key Finding

Mice drinking high-concentration hydrogen-rich water (0.8 mg H2/L) developed significantly less liver fat accumulation and gained less body fat than mice drinking regular water, even when fed a high-fat diet.

Summary

Researchers gave mice with a high-fat diet either regular water or water enriched with hydrogen gas (H2) to see if hydrogen could prevent fatty liver disease. Mice drinking high-concentration hydrogen water gained less fat, maintained more muscle, and had less fat buildup in their livers compared to mice drinking regular water. When liver cells from hydrogen-water-drinking mice were exposed to a fatty acid in the lab, they accumulated less fat than cells from mice drinking regular water, suggesting hydrogen provided direct protection.

Practical Takeaway

This mouse study suggests that molecular hydrogen may help protect against fatty liver disease caused by high-fat diets, but these are early findings in animals only. Human studies would be needed to determine whether hydrogen-rich water has similar effects in people. The study also found that hydrogen concentration matters—higher concentrations showed benefits while lower concentrations did not.

Abstract (excerpt)

AIM To identify the effect of hydrogen-rich water (HRW) and electrolyzed-alkaline water (EAW) on high-fat-induced non-alcoholic fatty acid disease in mice. METHODS Mice were divided into four groups: (1) Regular diet (RD)/regular water (RW); (2) high-fat diet (HFD)/RW; (3) RD/EAW; and (4) HFD/EAW…

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