Hydrogen Water Shows Promise for Dementia Prevention in Clinical Study
Effect of Hydrogen Water Drinking on Dementia Patient through Mechanism of Oxidative Stress and Immune Redox Balance
Research hubs: Brain & Nervous System · Immune System
- Evidence type
- Controlled trial (non-randomized) · Human study
- Authors
- Johny Bajgai, Jeong Eunsook, Cheol Su Kim, Ailyn Fadriquela, Dong-Heui Kim, Kyu-Jae Lee
- Journal
- Korean Journal of Waters
- Year
- 2019
- Study Type
- Human
- Delivery
- Water (Electrolysis)
- Dose
- hydrogen water for 6 months
- Duration
- 6 months
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- South Korea
TL;DR
Drinking hydrogen water may help reduce signs of dementia by lowering harmful proteins and inflammation in the body.
Key Finding
After 6 months of drinking hydrogen water, dementia patients showed significantly reduced serum amyloid-beta 40 levels and decreased inflammatory and oxidative stress markers compared to those drinking purified water.
Summary
Researchers gave dementia patients hydrogen water (water infused with hydrogen gas through electrolysis) or regular purified water for 6 months and measured various markers in their blood related to brain damage, inflammation, and oxidative stress (cellular damage from unstable molecules). They found that hydrogen water reduced levels of amyloid-beta 40 (a protein linked to Alzheimer's disease) and decreased markers of inflammation and oxidative stress compared to the control group.
Practical Takeaway
This early human study suggests hydrogen water may help reduce some biological markers associated with dementia, though the study's limitations—including unreported sample size and lack of cognitive testing results—mean more research is needed before drawing firm conclusions about its effects on actual memory or cognitive function in dementia patients.
Abstract (excerpt)
Hydrogen water (HW) which is produced by electrolysis of water has characteristics of extremely low oxidation-reduction potential (ORP) value and high dissolved hydrogen (DH). It has been proved to have various beneficial effects including antioxidant and anti-inflammatory effects; however, HW…