Electrolyzed Water + Special Dressing Speeds Burn Healing in Rats
- Authors
- Hua Xin, Ya-Juan Zheng, Nakae Hajime, Zhen-Guo Han
- Journal
- Chinese Journal of Traumatology
- Year
- 2003
- Study Type
- Rat
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- China
- Health Condition
- Third-Degree Burns
- Body System
- Integumentary System
TL;DR
A special water treatment followed by a sticky dressing speeds up skin healing in rat burn wounds.
Key Finding
In rats, burn wounds treated with electrolyzed oxidizing water followed by hydrocolloid occlusive dressing healed significantly faster than wounds treated with saline alone or no treatment.
Summary
This study tested whether electrolyzed oxidizing water (water treated with electricity to create reactive compounds) and special moisture-retaining bandages could speed up healing of severe burn wounds in rats. Researchers gave rats large burns and treated them four different ways: no treatment, saline rinse only, electrolyzed water rinse, or electrolyzed water rinse plus special bandages. The combination of electrolyzed water and bandages healed fastest, and all treated groups showed more immune cell activity and collagen buildup (signs of healing tissue) compared to untreated wounds.
Practical Takeaway
This is an animal-only study in rats, so results cannot be directly applied to humans. While the combination treatment showed promise in accelerating burn healing in this controlled setting, human studies would be needed to determine if electrolyzed water has similar effects on human burn wounds. The study does not address hydrogen water specifically, but rather water treated with electricity to create oxidizing compounds.
Abstract
Objective: To study the efficacy of electrolyzed oxidizing water (EOW) and hydrocolloid occlusive dressings in the acceleration of epithelialization in excised burn-wounds in rats. Methods: Each of the anesthetized Sprague-Dawley rats (n=28) was subjected to a third-degree burn that covered approximately 10% of the total body surface area. Rats were assigned into four groups: Group I (no irrigation), Group II (irrigation with physiologic saline), Group III (irrigation with EOW) and Group IV (hydrocolloid occlusive dressing after EOW irrigation). Wounds were observed macroscopically until complete epithelialization was present, then the epithelialized wounds were examined microscopically. Results: Healing of the burn wounds was the fastest in Group IV treated with hydrocolloid occlusive dressing together with EOW. Although extensive regenerative epidermis was seen in each Group, the proliferations of lymphocytes and macrophages associated with dense collagen deposition were more extensive in Group II, III and IV than in Group I. These findings were particularly evident in Group III and IV. Conclusions: Wound Healing may be accelerated by applying a hydrocolloid occlusive dressing on burn surfaces after they are cleaned with EOW.