Hydrogen Water Baths Reduce Psoriasis Symptoms in Mice Study
- Authors
- Xinyu Zhang, Pan Yu, Nan Hong, Fang Liu, Yuxin Shan, Yingying Wu, Binyi An, Hong Sang, Qingtao Kong
- Journal
- Experimental Dermatology
- Year
- 2023
- DOI
- 10.1111/exd.14872
- Study Type
- Mouse
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- China
- Health Condition
- Psoriasis
- Body System
- Integumentary
TL;DR
Bathing in hydrogen-rich water can reduce the severity of psoriasis in mice by decreasing inflammation and skin cell overgrowth.
Key Finding
Mice with psoriasis treated with hydrogen-rich water baths showed significantly reduced skin lesion severity and lower levels of inflammatory markers (IL-17, IL-23, TNF-α) and oxidative stress compared to control mice.
Summary
Researchers gave mice with psoriasis (a skin condition) baths in either hydrogen-rich water or regular water to see if hydrogen could help. Mice bathed in hydrogen-rich water had less severe skin damage, lower levels of inflammatory chemicals (substances that cause swelling and irritation), and less oxidative stress (cellular damage from unstable molecules) compared to mice given regular water baths.
Practical Takeaway
This is an early-stage animal study suggesting hydrogen-rich water may help reduce psoriasis symptoms, but it was only tested in mice, not humans. Before considering hydrogen baths as a psoriasis treatment, human clinical trials would be needed to confirm whether these results apply to people and to establish safe and effective protocols.
Abstract (excerpt)
AbstractThe purpose of this study was to investigate whether hydrogen‐rich bath has therapeutic effect on psoriasis and its molecular mechanism. Mice with imiquimod‐induced psoriasis were established and divided into groups. The mice were respectively treated with hydrogen‐rich water bath…