Hydrogen Gas Therapy for Brain Hemorrhage Patients Study Protocol
- Authors
- Fa Lin, Runting Li, Yu Chen, Jun Yang, Ke Wang, Yitong Jia, Heze Han, Qiang Hao, Guangzhi Shi, Shuo Wang, Yuanli Zhao, Xiaolin Chen
- Journal
- Trials
- Year
- 2024
- DOI
- 10.1186/s13063-024-08231-5
- Study Type
- clinical
- Peer Reviewed
- Yes
- Country
- China
- Health Condition
- Aneurysmal Subarachnoid Hemorrhage
- Body System
- Neurological
TL;DR
Doctors are testing whether breathing in a special mixture of hydrogen and oxygen gas can help people who have had a serious type of brain bleed recover better by preventing dangerous complications that happen days after the injury.
Summary
This is a study protocol (a plan for a future study) describing a clinical trial that will test whether breathing a mixture of hydrogen and oxygen gas can help patients who have suffered a ruptured brain aneurysm (a burst blood vessel in the brain). The study will compare patients who receive the hydrogen-oxygen mixture to those who receive oxygen alone, measuring whether the treatment prevents complications like reduced blood flow to the brain that commonly occur after this type of injury.
Practical Takeaway
This is a study protocol describing a planned trial, not a completed study with results, so there are no findings yet to apply. The HOMA trial aims to be the first large-scale test of hydrogen therapy in aneurysm patients, but consumers should wait for actual results before drawing any conclusions about whether this treatment works.
Abstract (excerpt)
Abstract Background Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening neurosurgical emergency with a high mortality rate. Delayed cerebral ischemia (DCI) and cerebral vasospasm (CVS) are delayed products of early brain injury (EBI), which may constitute the principal determinant…