Hydrogen Water + Ginseng Boosts Male Fertility in Mice Study
Combination of Korean Red Ginseng Extract and Hydrogen-Rich Water Improves Spermatogenesis and Sperm Motility in Male Mice
Research hubs: Reproductive System · Endocrine System
This research was done in animals. Results in animals often don't carry over to people.
- Evidence type
- Animal study (mouse)
- Authors
- Ja Yoon Ku, Min Jung Park, Hyun Jun Park, Nam Cheol Park, Bo Sun Joo
- Journal
- Chinese Journal of Integrative Medicine
- Year
- 2020
- PMID
- 31919748
- Study Type
- Mouse
- Participants
- 80
- Delivery
- Water (Dissolved)
- Dose
- 10 mL/kg daily hydrogen-rich water for 4 weeks
- Duration
- 4 weeks
- Outcome
- Positive
- Peer Reviewed
- Yes
- Cited by
- 25 (OpenAlex, as of November 2026)
- Country
- South Korea
TL;DR
Drinking a mixture of hydrogen-rich water and Korean Red Ginseng improved sperm count and movement in mice, especially older ones, by boosting antioxidant activity and sex hormone production.
Key Finding
A combination of hydrogen-rich water and Korean Red Ginseng extract synergistically improved sperm production and motility in male mice, with particularly strong effects in aged mice.
Summary
Researchers gave male mice a combination of hydrogen-rich water and Korean Red Ginseng extract for 4 weeks to see if it would improve sperm production and movement. The treatment increased sperm count and sperm motility (the ability of sperm to swim), and these effects were stronger when both ingredients were combined. The benefits were especially noticeable in older mice, where the treatment also boosted testosterone levels and reduced harmful molecules called reactive oxygen species in the blood.
Practical Takeaway
This is an early-stage animal study in mice, so results cannot be directly applied to humans. While the findings suggest hydrogen-rich water combined with ginseng may support male reproductive function through antioxidant mechanisms, human clinical trials would be needed to determine if similar benefits occur in men. The study does not provide evidence for use in humans at this time.
Abstract (excerpt)
Objective: To investigate the effect of hydrogen-rich Korean Red Ginseng (KRG) water (HRGW) mixture on the spermatogenesis and sperm motility of mice of different ages. Methods: Eighty young (3 month-old) and aged (12 month-old) male mice were randomly assigned to 4 groups (n =10 per group)…